| ㆍGeneral Introduction |
| Treatment of cough remains a clinical unmet need. Many of anticoughing agents shows dubious efficacy with no golden standard drug recognized in the market. Many of effective anticoughing agent are opioids, such as codeine, with narrow safety margin and significant side effects, which may ultimately prove to have limited utility in the treatment of cough. Need for cough and cold drug is increasing quite much Cough and Cold products innovations are wanted more and more including OTC drugs. No new anti-coughing agent development and appearance during the recent years. AHNGOOK developed non-opioid, peripherally acting anticoughing agent based on the theobromine for the first in the world. |
| ㆍMechanism of Action |
1. TRPV1 antagonist
Cough suppression by way of Inhibition of sensory nerve transduction in bronchial airway
2. PDE (phosphodiesterase)4 Inhibitor
Cough suppression by way of Dilation of Bronchial smooth muscle
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| ㆍIndication |
| the relief of cough symptoms caused by postnasal drip due to, rhinitis, sinusitis, nasopharyngitis also by the chronic bronchitis (indications of acute cough expected in 2010) |
| ㆍBusiness Type |
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